Taking certain drugs can be associated with the presence of psoriasis. The underlying pathogenesis can be controversial.
Drug-provoked psoriasis refers to the presence of psoriasis associated with drug exposure. This has 2 subtypes:
(1) drug-induced psoriasis
(2) drug aggravated psoriasis
|
Feature
|
Drug-Induced
|
Drug-Aggravated
|
|
personal or family history of psoriasis
|
no
|
yes
|
|
effects of stopping the drug
|
psoriasis regresses
|
psoriasis persists or progresses
|
|
pre-existing psoriatic lesions
|
none
|
exacerbated if present
|
Drugs associated with drug-provoked psoriasis include:
(1) lithium
(2) antimalarials
(3) antibiotics
(4) beta-blockers
(5) NSAIDs
(6) ACE inhibitors
(7) interferon
(8) terbinafine
(9) benzodiazepines
