Dressler's syndrome refers to pericarditis and/or pleuritis occurring after acute myocardial infarction. It occurs rarely today.



(1) recent history of myocardial infarction

(2) one or more of the following:

(2a) pericarditis with pericardial effusion and tamponade

(2b) pleuritis with pleural effusion

(2c) pneumonitis

(3) prolonged course if untreated

(4) exclusion of alternative diagnoses


Clinical presentation:

(1) chest pain

(2) fever

(3) pericardial or pleural rub


Factors increasing risk:

(1) treatment with an oral anticoagulant

(2) large, extensive infarct


Factors decreasing risk:

(1) aggressive therapy with steroids and other anti-inflammatory agents


Differential diagnosis:

(1) autoimmune

(2) infection


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