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Draize Ocular Irritation Score

Purpose:

To use the method of Draize et al to evaluate the ocular irritation caused by instilling a chemical compound into the conjunctival sac of a rabbit.

Specialty:

Clinical Pharmacology & Toxicology
Emergency Medicine & Critical Care
Emergency Medicine & Critical Care
Neurology, Psychiatry, Ophthalmology & Otolaryngology

Objective:

severity, prognosis, stage, adverse effects

ICD-10:

T26.9

Description:

Draize et al described a scale of weighted scores for grading the severity of ocular lesions in rabbits following exposure to a chemical agent. This is based on a modification of the scoring system of Friedenwald et al.

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