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Risk Factors for Cardiotoxicity Following Doxorubicin Therapy

Purpose:

To identify risk factors associated with doxorubicin cardiotoxicity.

Specialty:

Hematology Oncology
Cardiology

Objective:

risk factors, adverse effects

ICD-10:

T45.1

Description:

Doxorubicin (Adriamycin) is a commonly used antineoplastic agent whose dosage is limited by a dose-dependent congestive cardiomyopathy. The consequent congestive heart failure may occur during therapy, within a few weeks or even years later. This responds poorly to treatment and is associated with high mortality. Certain risk factors may increase the patient's sensitivity to developing myocardial injury.

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