Albendazole can be administered orally to treat patients with hydatid disease and neurocysticercosis.
Weight of the Patient |
Oral Dose |
Comments |
< 60 kilograms |
15 mg/kg/day divided for bid dosing with meals |
maximum total daily dose 800 mg |
>= 60 kilograms |
400 mg bid given with meals |
|
where:
• The dose of 800 mg a day is reached at 53.3 kilograms when dosed at 15 mg/kg. The dosing table given could be rewritten to use this as the cutoff point for patient weight.
Duration of therapy:
(1) neurocysticercosis: 8 to 30 days
(2) hydatid disease: 3 courses of therapy are recommended, with each cycle 28 days of therapy separated from the next cycle by a 14 day albendazole free interval
Patients with neurocysticercosis should also be considered for concurrent therapy with corticosteroids and/or anticonvulsants.
Specialty: Infectious Diseases, Pharmacology, clinical, Gastroenterology