Inada and Inagaki reported dose equivalence for short-acting antipsychotic agents in Japan. The authors are from Seiwa Hospital and Aoyama Gakuin University in Japan.
Drug
Oral Dose in mg
Parenteral Dose in mg
Ratio Oral to Parenteral Dose
haloperidol
10
5 (im/iv)
2
chlorpromazine
150
50 (im)
3
levomepromazine
100
25 (im)
4
sulpiride
200
50 (im)
4
perphenazine
10
2 (im)
5
prochlorperazine
35
5 (im)
7
timiperone
28
4 (im/iv)
7
olanzapine
10
9 (im)
1.111
NOTE: The dose equivalence relates to oral vs injectable, not between agents.
dose of parenteral form in mg =
= (oral dose) / (ratio of oral to parenteral dose)
dose of oral form in mg =
= (parenteral dose) * (ratio of oral to parenteral dose)
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