Description

Inada and Inagaki reported dose equivalence for drugs used to treat psychosis in Japan. The authors are from Seiwa Hospital and Aoyama Gakuin University in Japan.


Drug

Equivalent Dose

aripiprazole

4

blonanserin

4

bromperidol

2

carpipramine

100

chlorpromazine

100

clocapramine

40

clotiapine

40

clozapine

50

fluphenazine

2

haloperidol

2

levomepromazine

100

moperone

12.5

mosapramine

33

nemonapride

4.5

olanzapine

2.5

oxypertine

80

paliperidone

1.5

perazine

100

perospirone

8

perphenazine

10

pimozide

4

pipamperone

200

prochlorperazine

15

propericiazine

20

quetiapine

66

reserpine

0.15

risperidone

1

spiperone

1

sulpiride

200

sultropride

200

thioridazine

100

tiapride

100

timiperone

1.3

thiothixene

3.3

trifluoperazine

5

zotepine

66

 

where:

• Carpipramine, clotiapine, perazine, thioridazine, thiothixene and trifluoperazine are no longer available in Japan.

 

multiple of the equivalent dose =

= (actual dose) / (equivalent dose)

 

To convert to another drug in the table:

 

dose for new drug =

= (multiple of the equivalent dose for previous drug) * (equivalent dose for new drug)


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