Inada and Inagaki reported dose equivalence for drugs used to treat depression in Japan. The authors are from Seiwa Hospital and Aoyama Gakuin University in Japan.
Drug
Equivalent Dose
amitriptyline
150
amoxapine
150
clomiprazine
120
desipramine
150
dosulepin
150
duloxetine
30
escitalopram
20
fluvoxamine
150
imipramine
150
lofepramine
150
maprotiline
150
mianserin
60
milnacipran
100
mirtazapine
30
nortriptyline
75
paroxetine
40
paroxetine CR
50
safrazine
30
sertaline
100
setiptiline
6
sulpiride
300
trazodone
300
trimipramine
150
where:
• Desipramine and Safrazine are no longer available in Japan.
multiple of the equivalent dose =
= (actual dose) / (equivalent dose)
To convert to another drug in the table:
dose for new drug =
= (multiple of the equivalent dose for previous drug) * (equivalent dose for new drug)
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