The dose of low molecular weight (LMW) heparins and fondaparinux may need to be adjusted in renal insufficiency.
Parameters:
(1) creatinine clearance in mL/min
Creatinine Clearance
LMW Heparin Dose
>= 30 mL/min
100%
< 30 mL/min
70-75%
dialysis
50%
Fondaparinux
> 50 mL/min
20-50 mL/min
1.5 mg/day
< 20
do not use
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Specialty: Toxicology, Pharmacology, clinical, Emergency Medicine
