Donors weighing 110 pounds (50 kg) or more may donate the full 525 mL required for a routine donation (450 mL +/- 45 mL per unit + 30 mL for processing). If less than the regular amount is to be collected (due to low donor weight or other consideration), there is no need to reduce the amount of anticoagulant in the collection bag unless less than 300 mL is collected. If less than 300 mL is collected, then the amount of anticoagulant in the collection bag must be reduced.
