Nguyen et al developed the DOEScore to help identify postmenopausal women with low bone density. The authors are from Garvan Institute of Medical Research (Darlinghurst) and St. Vincent's Hospital (Sydney) in Australia.
DOES stands for the Dubbo Osteoporosis Epidemiology Study. Dubbo is a town northwest of Sydney that was the site of the study.
Parameters:
(1) age in years
(2) weight in kilograms
(3) history of fracture (presumably postmenopausal)
Parameter
Finding
Points
age in years
< 70
1
70 - 79
2
80 - 84
3
>= 85
4
body weight in kg
>= 90 kg
1
80 - 89 kg
2
75 - 79 kg
3
70 - 74 kg
4
65 - 69 kg
6
60 - 64 kg
8
55 - 59 kg
11
< 55 kg
16
history of previous fracture
no
1
yes
2
where:
• The data is from Table 4, page 52. There are numerous errors in both Tables 3 and 4. The points for weights >= 80 kg are listed under age.
• The risk of low bone density increases with lower weight. The values in the table were reversed since the shown values are the opposite of the intuitive values.
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 3
• maximum score: 22 (in the text the highest score is given as 36 on page 52).
• A score >= 10 was associated with a low bone density (T score < -2.5) in the femoral neck and lumbar spine.
Limitations:
• The cutoff gave a sensitivity of 82% and specificity of 52% for low bone mineral density.
• The score is not particularly useful for identifying which women will have a fracture.
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