Chandel et al reported the DO-GAP score to evaluate a patient with idiopathic pulmonary fibrosis (IPF). The authors are from Walter Reed National Military Medical Center, Hopital European Georges Pompidou and Inova Fairfax Hospital.
DO-GAP is named for the parameters of the score.
Patient selection: idiopathic pulmonary fibrosis
Parameters:
(1) distance in 6MWT in meters (D)
(2) oxygenation as hypoxia (O)
(3) gender (G)
(4) age in years (A)
(5) physiology as percent of predicted (P) for FVC and DLCO
Parameter
Finding
Points
distance in 6MWT
< 250 meters
5
>= 250 meters
0
oxygenation
no hypoxia
0
exertional hypoxia
5
gender
female
0
male
1
age in years
<= 60 years
0
61 to 65 years
1
> 65 years
2
FVC as percent of predicted
> 75%
0
50 to 75%
1
< 50%
2
DLCO2 as percent of predicted
> 55%
0
36 to 55%
1
<= 35%
2
cannot perform
3
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 18
Score
Stage
3-Year Mortality
0 to 4
Stage I
16%
5 to 10
Stage II
36%
11 to 18
Stage III
73%
Performance:
• The area under the ROC curve was 0.75 for internal validation.
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