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Distinguishing Acute Promyelocytic Leukemia (APML) from the Recovery Phase of Acute Agranulocytosis Using CD117 and CD11b Immunostaining of the Bone Marrow

Specialty:

Hematology Oncology

Objective:

ICD-10:

Description:

The morphologic appearance of the bone marrow in a patient with acute promyelocytic leukemia (APML) may be very similar to that of a patient with benign myeloid proliferation in the recovery phase following acute agranulocytosis. The staining pattern of promyelocytes to CD117 and CD11b can help distinguish between these 2 conditions. The authors are from the University of Sao Paulo in Brazil.

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