Description

Cappellini et al for developed a Disease Severity Scoring System (DSSS) for patients with non-transfusion-dependent thalassemia (NTDT). The final score was the sum of several subscores.The authors are from the University of Milan, University College London, American University of Beirut, University of Athens, Mahidol University (Bangkok) and the University of Cagliari.


 

Patient selection: non-transfusion-dependent thalassemia (NTDT)

 

Subscore

Maximum Points

hematological and iron status

9

liver status

12

cardiovascular status

12

comorbid status

19

pediatric (<= 16 years of age)

10

 

total score =

= SUM(points for all subscores)

 

Interpretation:

• minimum total score: 0

• maximum score for a pediatric patient: 62

• maximum score for an adult: 52

• The higher the score the more severe the disease.

 


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