Description

Consolaro et al developed 3 Juvenile Arthritis Activity Scores (JADAS) with different numbers of joints counted. The simplest version was the JADAS-10 which had 4 items. This was used as the basis for a 3 item cJADAS10. The authors are from multiple institutions in Italy.


Patient selection: juvenile arthritis

 

The 3 item cJADAS10 is based on the 4 item JADAS10, with removal of the ESR.

 

Parameters:

(1) number of joints affected, up to a maximum of 10

(2) physician assessment on a 10 cm VAS scale

(3) patient assessment on a 10 cm VAS scale

 

points for joints affected =

= MIN(10, (number of joints affected)

 

The minimum cJADAS10 was 0 and the maximum 30.

 

If 1 to 4 joints are affected then the designation is oligoarthritis.

 

If 5 or more joints are affected then the designation is polyarthritis.

 

Disease Activity

Designation

Criteria

inactive

ID

no joints with active disease; no systemic manifestations attributable to JIA; no active uveitis; normal concentrations of acute phase reactants; physician global VAS 0 cm; duration of morning stiffness less than 15 minutes

minimal or low

LDA

For polyarthritis: physician's global VAS <= 3.5 cm; parent's or patient's global VAS <= 2.5 cm; swollen joint count <= 1. For oligoarthritis: physician's global VAS <= 2.5 cm; swollen joint count 0.

moderate activity

MDA

not ID, LDA or HDA

high activity

HDA

therapy as listed see below

 

 

Therapy for HDA

Oligoarthritis (one or more)

Polyarthritis (one or more)

intra-articular injection corticosteroids

>= 1 joint

>= 3 joints

DMARD

start

start

biological agent

start

start

systemic steroids

NA

start

 

 

Disease Activity

Oligoarthritis

Polyarthritis

ID

cJADAS10 <= 1

cJADAS10 <= 1

LDA

cJADAS10 <= 1.5

cJADAS10 <= 2.5

MDA

cJADAS10 1.51 to 4.00

cJADAS10 2.51 to 8.50

HDA

cJADAS10 > 4.00

cJADAS10 > 8.50

 

where:

• For oligoarthritis ID and LDA the joint count should be 0. For polyarthritis LDA the joint count should be 0 or 1.


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