Ross and Linch listed discriminant indices for clinical findings that can help identify an obese patient with Cushing's syndrome. The authors are from University College London.
discriminant index =
= (prevalence of finding in Cushing's syndrome) / (prevalence in obese patient without Cushing's syndrome)
High discriminant index (8.0 to 10.3):
(1) bruising
(2) myopathy
Intermediate discriminant index (2.5 to 4.4):
(1) hypertension
(2) plethora
(3) ankle edema
(4) hirsutism in a woman
(5) red striae
Slightly increased discriminant index (1.3 to 1.6):
(1) menstrual irregularity in a woman
(2) truncal obesity
(3) headache
where:
• I am not sure why moon facies and buffalo hump are not listed.
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