An increase in plasma fibrin degradation products can be seen in a number of conditions, some of which may co-exist.

Conditions that may be associated with elevation in fibrin degradation products:

(1) disseminated intravascular coagulation (DIC)

(2) thrombosis

(3) trauma or recent surgery

(4) hematoma

(5) massive hydrothorax/ascites

(6) fibrinolytic therapy

(7) liver impairment

(8) renal impairment

(9) malignancy

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