Rarely crystals can be seen in a colon biopsy.
Endogenous causes of mucosal crystals:
(1) Charcot-Leyden crystals (with eosinophilic infiltrate)
(2) cholesterol crystals from atheroemboli
Exogenous crystals:
(1) oxlate following ethylene glycol poisoning
(2) extravasated chemical from enema (barium, sodium polystyrene sulfonate, other)
(3) Sevelamer or other drug crystals
(4) drugs or chemicals administered per rectum
Differential diagnosis:
(1) in vitro artifact during handling or processing
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Specialty: Gastroenterology
ICD-10: ,
