A patient with lung cancer may develop bradycardia. This may be a result of one or more causes.

Patient selection: lung cancer with bradycardia


Differential diagnosis:

(1) paraneoplastic dysautonomia (small cell lung cancer with anti-Hu, other)

(2) brain metastases with increased intra-cranial pressure

(3) carotid sinus disorder

(4) intermittent great vessel obstruction

(5) chemotherapy effect (immune checkpoint inhibitor related myocarditis, crizotinib, irinotecan)

(6) vasovagal reflex

(7) acute myocardial infarction

(8) medications (beta-blockers and/or calcium channel blockers)

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