Commonly considered conditions:
(1) verruca/condyloma (wart)
(2) verrucous squamous cell carcinoma
(3) verrucous squamous cell leukoplakia
(4) verrucous squamous cell hyperplasia
Other conditions to consider:
(1) verrucous lichen planus
(2) verrucous lupus erythematosus
(3) verruciform xanthoma
(4) verrucous sarcoidosis
(5) verrucous hemangioma/vascular malformation/angiokeratoma
(6) verrucous epidermal nevus
(7) verrucous seborrheic keratosis
(8) verrucous variant of porokeratosis of Mibelli
(9) acral microcystic lymphangioma
(10) dermal leishmaniasis
(11) verrucous sporotrichosis or histoplasmosis
plus others
A superficial shave biopsy may only show the surface keratin without showing the underling process. This can be significant in a verrucous carcinoma.