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Diagonal Ear Lobe Crease (Frank's Sign, Aural Sign)

Specialty:

Dermatology
Otolaryngology

Objective:

ICD-10:

Description:

Frank described diagnonal creases on the ear lobe. He considered this a possible sign of coronary artery disease (CAD). It has been hypothesized that creases are due to changes in subcutaneous microvasculature occurring at the same time as vascular changes in the heart.

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