Lereuz-Ville et al used a simple diagnostic tree to evaluate a neonate or fetus for likelihood of a symptomatic cytomegalovirus (CMV) infection. The authors are from Universite Paris Descartes, Assistance publique-Hopitaux de Paris, Hopital Necker-Enfants Malades Paris, Poissy Hospital, Hopital Intercommunal de Poissy-Saint Germain and Hopital Americain de Paris.
Patient selection: fetus or neonate of woman with evidence of a CMV infection during the pregnancy
Analysis: recursive partitioning
Parameters:
(1) platelet count per µL
(2) CMV DNA in fetal blood, in LOG10 IU/mL
Platelet Count
LOG10 CMV DNA
Percent Symptomatic CMV
<= 114,000 per µL
NA
63%
> 114,000 per µL
< 4.93 IU/mL
3%
> 114,000 per µL
>= 4.93 IU/mL
57%
whereL
• LOG10 4.93 corresponds to a count of 85,114 IU/mL
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