Description

Mortazavi et al reported a diagnostic decision tree to aid in the diagnosis of an oral white lesion. The authors are from Shahid Beheshti University of Medical Sciences in Iran.


Patient selection: oral white lesion

 

Parameters:

(1) congenital vs acquired

(2) scrapability

(3) specific pattern

 

Congenital vs Acquired

Can Be Scraped Off

Specific Pattern

Group

congenital

NA

NA

1

acquired

Yes

NA

2

acquired

No

Yes

3

acquired

No

No

4

 

Group 1:

(1) leukoedema

(2) white sponge nevus

(3) dyskeratosis congenita

(4) hereditary benign intraepithelial dyskeratosis

 

Group 2:

(1) superficial oral burn

(2) pseudomembranous candidiasis

(3) pseudomembrane of oral ulcers and materia alba

(4) habitual biting of cheek, lips and tongue (morsicatio)

 

Group 3:

(1) lichenoid

(1a) oral lichen planus

(1b) lichenoid contact reaction

(1c) drug-induced lichenoid reaction

(1d) graft-vs-host disease (GVHD)

(2) lupus erythematosus

 

Group 4:

(1) frictional keratosis

(2) oral leukoplakia

(3) oral hairy leukiplakia

(4) proliferative verrucous leukoplakia

(5) oral squamous cell carcinoma

(6) verrucous carcinoma

(7) nicotinic stomatitis

(8) actinic keratitis

(9) candidiasis (chronic mucocutaneous vs chronic hyperplastic)

(10) other


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