The Neurosarcoidosis Consortium Consensus Group listed criteria for the diagnosis of neurosarcoidosis. The authors are from multiple institutions in the United States and Europe.
Neurosarcoidosis may be limited to the CNS (type b) or involve both the nervous system and extraneural sites (type a).
Parameters:
(1) clinical evidence
(2) pathologic confirmation
Clinical Evidence
Pathologic Confirmation
Neurosarcoidosis
suggestive
positive in CNS
definite
suggestive
positive in extra-CNS
probable
suggestive
none or negative
possible
Clinical evidence is based on:
(1) clinical manifestations
(2) MRI, CSF, EMG/NCS (electromyogram, nerve conduction studies) consistent with granulomatous inflammation of the CNS
(3) rigorous exclusion of other conditions in the differential diagnosis
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