Diagnostic Critera of the European Respiratory Society (ERS) for Lymphangioleiomyomatosis

The European Respiratory Society (ERS) has published diagnostic criteria for lymphangioleiomyomatosis (LAM).

Parameters:

(1) clinical history compatible with LAM

(2) high resolution computed tomography (HRCT) of the lungs

(3) tuberous sclerosis complex (TSC)

(4) renal angiomyolipoma

(5) thoracic and/or abdominal chylous effusion

(6) lymphangioleiomyomatosis (LAM) in a lung biopsy

(7) lymphangioleiomyoma (LAM) not in lung

Pulmonary HRCT	Other Finding	LAM in Female
characteristic	LAM in lung biopsy	definite
compatible	LAM in lung biopsy	definite
characteristic	renal angiomyolipoma	definite
characteristic	thoracic or abdominal chylous effusion	definite
characteristic	LAM other than lung	definite
characteristic	TSC (definite or probable)	definite
characteristic	clinical history	probable
compatible	renal angiomyolipoma	probable
compatible	thoracic or abdominal chylous effusion	probable
characteristic	NA	possible
compatible	NA	possible

The diagnosis of LAM requires exclusion of alternative causes of cystic lung disease.

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