Description

Daghor-Abbaci et al reported an algorithm for the diagnosis of Adult-Onset Still's Disease (AOSD). The authors are from multiple institutions in Algeria.

 


Patient selection: adult suspected of having Adult-Onset Still's disease

 

Parameters:

(1) typical rash

(2) elevated body temperature in °C >= 2 weeks

(3) arthritis lasting >= 2 weeks

(4) pharyngitis

(5) neutrophil to lymphocyte ratio (NLR)

(6) ferritin and glycosylated ferritin

 

Parameter

Finding

Points

typical rash

no

0

 

yes

3

body temperature

>= 39°C for >= 2 weeks

3

 

other

0

arthritis

present for >= 2 weeks

2

 

other

0

pharyngitis

no

0

 

yes

2

NLR

< 4

0

 

>= 4

2

ferritin and glycosylated ferritin

ferritin elevated with glycosylated <= 20%

1

 

other

0

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 13

• A score >= 7 indicates Adult-Onset Still's Disease

 

Performance:

• At the cut-off the sensitivity was 0.93 and specificity 0.93.

• The area under the ROC curve was 0.97.


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