Zoster Sine Herpete refers to Herpes zoster without the skin rash.
Features:
(1) reactivation of Varicella zoster virus within the dorsal root ganglia.
(2) failure to develop any skin changes
(3) severe radicular pain
Diagnosis can be difficult and often requires a high level of clinical suspicion. Sophisticated virologic testing is required to confirm the diagnosis.
It is presumably related to a level of immunocompetence that is capable of partially checking the viral reactivation.
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