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Diagnosis of Vitamin B12 Status Using Holotranscobalamin (HoloTC)

Specialty:

Endocrinology, Nutrition & Dermatology

Objective:

ICD-10:

Description:

Diagnosis of vitamin B12 deficiency can be difficult, especially in the elderly. Methylmalonic acid (MMA) concentrations may be affected by renal dysfunction. Valente et al recommended the use of holotranscobalamin (holoTC) as a screening test for detection of vitamin B12 deficiency.

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