A neonate with Persistent Pulmonary Hypertension of the Newborn (PPHN) presents with a number of clinical findings.
(1) severe postnatal hypoxemia
(2) severe respiratory failure require intubation and mechanical ventilation
(1) a persistent elevation of pulmonary vascular resistance
(2) a persistent elevation in right ventricular pressure
(3) a right-to-left shunt through a patent foramen ovale and/or a patent ductus arteriosus
(4) an elevated serum BNP
Exclusion: The changes are not due to another congenital anomaly.
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