Exalto et al developed a score for predicting the risk of diabetes-related dementia in an adult within 10 years. This can help to identify a patient who may benefit from more aggressive management. The authors are from University Medical Centre Utrecht, Kaiser Permanente, University of Chicago and University of Washington Seattle.
Patient selection: Type 2 diabetes mellitus >= 60 years of age
Parameters:
(1) age in years
(2) education
(3) acute metabolic event
(4) microvascular disease
(5) diabetic foot
(6) cerebrovascular disease
(7) cardiovascular disease
(8) depression
Parameter
Finding
Points
age in years
60 to 64 years
0
65 to 69 years
3
70 to 74 years
5
75 to 79 years
7
80 to 84 years
8
>= 85 years
10
education
<= 12 years (high school)
0
any college
-1
acute metabolic event
no
0
yes
2
microvascular disease
no
0
yes
1
diabetic foot
no
0
yes
1
cerebrovascular disease
no
0
yes
2
cardiovascular disease
no
0
yes
1
depression
no
0
yes
2
total score =
= SUM(points for all 8 parameters)
Interpretation:
• minimum score: -1
• maximum score: 19
• The higher the score the greater the risk for diabetes-related dementia.
Total Score
Percent Dementia
-1
5%
0
7%
1
10%
2
13%
3
15%
4
21%
5
25%
6
34%
7
40%
8
50%
9
58%
10
63%
11
66%
12 to 10
73%
Performance:
• The area under the ROC curve is 0.73.
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