Intracardiac and pulmonary thromboembolism (ICPTE) can result in death within 24 hours of a liver transplantation. Fukazawa et al reported an index to help to identify a patient at risk. The authors are from the University of Washington, University of Miami, Westchester Medical Center and Allegheny General Hospital.
Patient selection: liver transplant for end-stage liver disease
Outcome: devastating intracardiac and pulmonary thromboembolism
Parameters:
(1) ethnicity
(2) diabetes
(3) portal vein thrombosis
(4) pulmonary embolism
(5) ventilator support
(6) functional status (by Karnofsky performance status) from 10 to 100
Parameter
Finding
Points
ethnicity
Asian
LN(3.706) = 1.31
other
0
diabetes
no
0
yes
LN(1.969) = 0.678
portal vein thrombosis
no
0
yes
LN(2.958) = 1.085
pulmonary embolism
no
0
yes
LN(32.023) = 3.466
ventilator support
no
0
yes
LN(2.737) = 1.007
KPA
<19
LN(3.108) = 1.134
>= 19
0
where:
• LN(N) indicates conversion of the odds ratio N to the beta-ceofficient
value of X =
= SUM(points for all of the parameters)
DICPTEI =
= EXP(X)
Interpretation:
• minimum DICPTEI: 1
• maximum SICPTEI: 5,884
Performance:
• The area under the ROC curve is 0.70.
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