Pongpan et al reported the Dengue Infection Severity Score which can help to determine the severity of dengue in a patient. The authors are from Chiang Mai University, Sawanpracharak Hospital and Phrae Hospital in Thailand.
Patient selection: dengue fever
Parameters:
(1) age in years
(2) hepatomegaly
(3) hematocrit in percent
(4) systolic blood pressure in mm Hg
(5) white blood cell count per microliter
(6) platelet count per microliter
Parameter
Finding
Points
age in years
> 6 years old
1
<= 6 years old
0
hepatomegaly
yes
8.5
no
0
hematocrit
>= 40
1
< 40
0
systolic blood pressure
< 90 mm Hg
2
>= 90 mm Hg
0
WBC count
> 5,000 per µL
1
<= 5,000 per µL
0
platelet count
<= 50,000 per µL
4.5
> 50,000 per µL
0
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 18
Score
Severity Level
< 2.5
dengue fever (DF)
2.5 to 11.5
dengue hemorrhagic fever (DHF)
> 11.5
dengue shock syndrome (DSS)
Performance:
• A patient was correctly classified in 61%.
• The rate of underestimation was 25% and overestimation was 14%.
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