Liu and Harrington identified factors in the delivery room that are associated with Meconium Aspiration Syndrome (MAS). These can help to identify a neonate who may require more aggressive management. The authors are from Children's Hospital of Southwest Florida.

Patient selection: neonate in the delivery room


Risk factors for meconium aspiration syndrome from multivariate analysis:

(1) fetal distress

(2) Apgar at 1 minute < 7

(3) Apgar at 5 minutes < 7

(4) thick meconium


If none of these factors are present then the risk is less than 1%.

If all 4 are present then the risk is 80%.


Additional risk factors from bivariate analysis:

(1) need for resuscitation

(2) stomach suction performed at < 5 minutes of age


The presence of tracheal meconium was highly prevalent and was not predictive of MAS.

To read more or access our algorithms and calculators, please log in or register.