The Ad Hoc Task Force of the International League Against Epilepsy (ILAE) developed a definition for drug-resistant epilepsy.
Patient selection: seizure disorder
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Criteria
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Comment
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failure to achieve a sustained freedom from seizures
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patient still having seizures despite therapy
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adequate trials
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the dose was right and the drug was given long enough to see if it would work
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two anticonvulsant drugs tried
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may be used in sequence (A then B) or in combination (A and B)
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tolerated
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drugs not discontinued because of intolerable side effects
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appropriately chosen
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drugs selected for the type of seizure
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used
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failure not due to nonadherence
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