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Deficiency in ADAMTS13 and Thrombotic Thrombocytopenic Purpura

Specialty:

Hematology Oncology
Clinical Laboratory

Objective:

ICD-10:

Description:

Thrombotic Thrombocytopenic Purpura (TTP) is associated with formation of microthrombi in the microcirculation. A deficiency in the protein ADAMTS13 has been found in patients with TTP and is believed to be fundamental in its pathogenesis.

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