Deficiency in ADAMTS13 and Thrombotic Thrombocytopenic Purpura
Specialty: | Allergy, Immunology, Anesthesiology, Cardiology, Dermatology, Endocrinology, Diabetes, Metabolism, Emergency Medicine, Family, General Practice, Geriatrics, Internal Medicine, Medical Genetics, Neurological Surgery, Neurology, Obstetrics, Gynecology, Oncology, Ophthalmology, Orthopedics, Otolaryngology, Pathology, Pediatrics, Physical Medicine and Rehabilitation, Plastic Surgery, Preventive Medicine, Psychiatry, Radiology, Surgery, Urology, Other |
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Description: | Thrombotic Thrombocytopenic Purpura (TTP) is associated with formation of microthrombi in the microcirculation. A deficiency in the protein ADAMTS13 has been found in patients with TTP and is believed to be fundamental in its pathogenesis. |
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