Esteban et al reported a classification and regression tree (CART) for patients with stable COPD. The authors are from the University of Basque Country and Hospital de GaldakaoUsansolo in Spain.
Patient selection: stable COPD
Outcome: 5-year mortality risk
Parameters:
(1) age in years
(2) FEV1 as percent of predicted
(3) dyspnea severity from 1 to 4 (Fletcher et al, 1 = after vigorous exercise, 4 = at rest or minimal exertion)
(4) past hospitalization for COPD exacerbation
(5) physical activity (very low, low, moderate, high)
For patients >= 75 years
Dyspnea Severity |
FEV1 |
Past Hospital |
Physical Activity |
Mortality Risk |
1 or 2 |
NA |
0 or 1 |
M or H |
12.1% |
1 or 2 |
NA |
0 or 1 |
VL or L |
45.2% |
1 or 2 |
NA |
>= 2 |
NA |
85.7% |
3 or 4 |
> 49% |
NA |
NA |
52.2% |
3 or 4 |
<= 49% |
NA |
NA |
74.4% |
For patients < 75 years
Age |
FEV1 |
Dyspnea |
Past Hospital |
Physical Activity |
Mortality Risk |
<55 |
>= 35% |
NA |
<= 1 |
NA |
4.4% |
55 to 74 |
> 65% |
NA |
NA |
NA |
7.7% |
55 to 74 |
35 to 65% |
NA |
<= 1 |
H |
10.5% |
55 to 74 |
35 to 65% |
NA |
<= 1 |
L or M |
16.9% |
55 to 74 |
35 to 65% |
NA |
<= 1 |
VL |
30.8% |
< 75 |
> 65% |
NA |
> 1 |
NA |
14.3% |
< 75 |
35-65% |
NA |
> 1 |
M or H |
27.3% |
< 75 |
35-65% |
NA |
> 1 |
VL or L |
65% |
< 75 |
< 35% |
1 or 2 |
0 |
NA |
18.2% |
< 75 |
< 35% |
1 or 2 |
>=1 |
NA |
42.9% |
< 75 |
< 35% |
3 or 4 |
NA |
NA |
60.4% |
Specialty: Pulmonology