Description

Kiewiet et al reported a decision rule for a patient with secondary abdominal sepsis following initial surgery. This can help to identify a patient with ongoing infection. The authors are from the Academic Medical Centre in Amsterdam.


Patient selection: secondary peritonitis following initial surgical management

 

Parameters:

(1) contamination

(2) defecation

(3) inotropic medications

(4) body temperature in °C

(5) heart rate in beats per minute

(6) hemoglobin in mmol/L (the conversion factor from g/dL to mmol/L appears to be 0.6206).

Parameter

Finding

Points

Beta-Coefficient

contamination

local

0

0

 

diffuse

7

0.76695

defecation

no

14

1.46956

 

yes

0

0

inotropic meds

no

0

0

 

yes

14

1.40856

body temperature

< 35.5°C

9

0.91645

 

35.5 to 39°C

0

0

 

> 39°C

9

0.91645

heart rate

<= 90 bpm

0

0

 

> 90 bpm

6

0.67818

hemoglobin

<= 5 mmol/L (8.1 g/dL)

10

1.09552

 

> 5 mmol/L

0

0

 

total score =

= SUM(points for all 6 parameters)

 

X =

= SUM(beta coefficients) - 4.412803 (original)

= SUM(beta coefficients) - 3.135282 (updated)

 

probability of persistent sepsis =

= 1 / (1 + EXP((-1) * X))

 

Interpretation:

minimum score: 0

maximum score: 60

The higher the score the greater the risk of ongoing peritonitis.

 

Total Score

Risk Group

Abdominal Sepsis

0 to 20

low

11%

21 to 40

intermediate

35%

> 40

high

67%

 

 

Risk Group

Perform CT

Repeat Decision Rule

low

no

24 hours

intermediate

consider

12 hours

high

yes

12 hours if CT negative

 

Performance:

The area under the ROC curve is 0.80.


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