Hentzien et al reported the Dat'AIDS score for evaluating an older adult living with HIV. The authors are from multiple institutions in France.
Patient selection: HIV-positive adult >= 60 years old
Parameters:
(1) age in years
(2) CD4 cell count
(3) non-HIV related cancer
(4) cardiovascular disease
(5) eGFR in mL per min per 1.73 square meters by CKD-EPI formula
(6) cirrhosis
(7) body mass index (BMI)
(8) anemia (hemoglobin < 12 g/dL for female; hemoglobin < 13 g/dL for male)
Parameter
Finding
Points
age in years
60 to 64 years
0
65 to 74 years
1
>= 75 years
8
CD4 cell count
>= 350 per µL
200 to 349 per µL
3
< 200 per µL
6
non-HIV related cancer
no
yes
cardiovascular disease
eGFR
>= 60 mL/min/1.73 sq m
30 to 59
5
< 30 mL/min/1.73 sq m
16
cirrhosis
13
BMI
normal or high
low (< 18.5 kg per sq m)
10
anemia
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 73
survival probability for x years =
= (1 - (0.00562 * (x)) - (0.00057679 * (x^2)))^(EXP(0.1008354015*(score)))
Performance:
• The area under the ROC curve is 0.76.
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Specialty: Infectious Diseases
