Description

Remy-Jardin et al studied the lungs of cigarette smokers with normal chest X-rays and pulmonary function tests using high resolution CT (HRCT). They were able to identify a number of findings that are seen in current or ex-smokers. The authors are from the University of Lille in Lille, France.


 

Imaging studies: high resolution CT

 

HRCT Finding

Features

parenchymal micronodules < 7 mm in diameter

represent respiratory bronchiolitis; detected more often in the upper lung zones

areas of ground-glass attenuation

areas that are slightly hyperattenuated, with underlying vessels and bronchial walls still visible; represent areas of inflammation within the alveoli; detected more often in the upper lung zones

emphysema

areas of decreased attenuation and disruption of the vascular pattern, usually lacking a well-defined wall; detected more often in the upper lung zones

dependent areas of attenuation

seen in the posterior lung when supine but disappear when the patient is supine

bronchial wall thickening

central bronchus with wall thickness >= 2 times wall thickness of normal bronchus; peripheral bronchus with well-delineated bronchial walls

septal lines

thickened interlobular septa identified as fine linear areas of attenuation or as a polygonal pattern of multiple polygonal lines

subpleural micronodules < 7 mm in diameter

represent subpleural interstitial anthracosis

 

where:

• Nodules >= 7 mm may be seen on routine chest X-ray.

• The patient should be in a typical state of health. Bronchopneumonia or other active lung infection would affect the findings.

 

Findings seen more commonly in smokers:

(1) ground glass attenuation

(2) emphysema

 

Findings seen more commonly in smokers or ex-smokers:

(1) parenchymal micronodules

(2) bronchial wall thickening

(3) dependent areas of attenuation

 

Findings seen in smokers, ex-smokers and non-smokers:

(1) subpleural micronodules

(2) septal lines

 

Changes on CT

Nonsmokers

Exsmokers

Smokers

normal CT

57%

37%

17%

1 or 2 CT changes

38%

50%

50%

>= 3 CT changes

5%

13%

33%

from Figure 5. page 113

 


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