Cryptococcus species may occasionally infect bone, even in immunocompetent patients.
On imaging there is a lytic lesion in the affected bone.
The patient may be otherwise asymptomatic or the patient may have:
(1) fever or other systemic signs
(2) a lung nodule
(3) lymphadenopathy
In an older adult the bone lesion may be initially diagnosed as metastatic cancer.
The diagnosis is made by:
(1) histology
(2) fungal culture
(3) serum antigen testing
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Specialty: Infectious Diseases
