### Description

Subherwal et al developed the CRUSADE bleeding score to identify a patient at risk for major in-hospital bleeding following therapy on non-ST-segment elevation myocardial infarction. The authors are from Washington University, Duke University, University of Cincinnati and Pennsylvania Hospital.

CRUSADE = Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHH guidelines.

Parameters:

(1) baseline hematocrit in percent

(2) estimated creatinine clearance in mL per minute (Cockcroft-Gault)

(3) heart rate in beats per minute

(4) gender

(5) signs of congestive heart failure (CHF) at presentation

(6) history of prior vascular disease (stroke or peripheral artery disease)

(7) history of diabetes mellitus

(8) systolic blood pressure in mm Hg

Parameter

Finding

Points

baseline hematocrit

< 31%

9

31.0 to 33.9%

7

34.0 to 36.9%

3

37.0 to 39.9%

2

>= 40%

0

creatinine clearance

<= 15 mL per minute

39

15.1 to 30

35

30.1 to 60

28

60.1 to 90

17

90.1 to 120

7

> 120 mL per minute

0

heart rate

<= 70 beats per minute

0

71 to 80

1

81 to 90

3

91 to 100

6

101 to 110

8

111 to 120

10

> 120

11

gender

male

0

female

8

signs of CHF

no

0

yes

7

history of vascular disease

no

0

yes

6

history of diabetes mellitus

no

0

yes

6

systolic blood pressure

<= 90 mm Hg

10

91 to 100

8

101 to 120

5

121 to 180

1

181 to 200

3

>= 201 mm Hg

5

total score =

= SUM(points for all 8 parameters)

Interpretation:

• minimum score 1

• maximum score: 96 points

Score

Percent Major Bleeding

0 to 50

(0.002554 * ((points)^2)) + (0.06432 * (points)) + 2.418

50 to 100

(0.005616 * ((points)^2)) - (0.21 * (points)) + 8.579

0 to 100

(0.000020 * ((points)^3)) + (0.001311 * ((points)^2)) + (0.07947 * (points)) + 2.42