Crohn’s disease may involve several extraintestinal sites, including the vulva. Delay in diagnosis or misdiagnosis are common.


Involvement of the vulva may precede or follow the onset of small bowel involvement.


Clinical findings:

(1) labial swelling

(2) erythema and induration

(3) variable ulceration

(4) pain and tenderness


Involvement may be unilateral or bilateral


Granulomatous vulvitis can be seen on biopsy.


The lesions respond to infliximab or other Crohn’s therapy.


The diagnosis requires exclusion of other diagnoses.


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