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Description

Stachon et al developed the Critical Risk Evaluation by Early Keys (CREEK) Score for predicting mortality for a patient in the medical intensive care unit. This can help to identify a patient who may benefit from more aggressive management (versus a patient who is up the CREEK without a paddle). The authors are from Ruhr University in Bochum, Germany.


Parameters:

(1) ALT in IU/L

(2) total cholesterol in mg/dL

(3) serum creatinine in mg/dL

(4) white blood cell count in 10^9/L

(5) serum sodium in mmol/L

(6) thrombocytosis

(7) thrombocytopenia

(8) BUN in mg/dL

(9) age in years

 

Parameter

Finding

Points

ALT in IU/L

ALT in IU/L

LN(ALT)

cholesterol

cholesterol in mg/dL

ABS((cholesterol) - 225)

creatinine

<= 1.2 mg/dL

0

 

> 1.2 mg/dL

1

WBC

as multiple of 10^9/L

ABS((WBC) - 7.5)

sodium

>= 131 mmol/L

0

 

< 131 mmol/L

1

thrombocytosis

<= 350 * 10^9/L

0

 

> 350 * 10^9/L

1

thrombocytopenia

>= 150 * 10^9/L

0

 

100 to 149 * 10^9/L

1

 

50 to 99 * 10^9/L

2

 

< 50 * 10^9/L

3

BUN

<11 mg/dL

0

 

11 to 20 mg/dL

1

 

21 to 30 mg/dL

2

 

> 30 mg/dL

3

age

age in years

(years)

 

where:

• Several of the parameters are measures of organ failure.

 

X =

= (0.3942 * (points for ALT)) + (0.00999 * (points for cholesterol)) + (0.8133 * (points for creatinine)) + (0.0616 * (points for WBC count)) + (1.0227 * (points for sodium)) + (1.1881 * (points for thrombocytosis)) + (0.7783 * (points for thrombocytopenia)) + (0.3831 * (points for BUN)) + (0.0422 * (points for age)) - 8.6435

 

mortality risk =

= 1 / (1 + EXP((-1) * X))


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