Stachon et al developed the Critical Risk Evaluation by Early Keys (CREEK) Score for predicting mortality for a patient in the medical intensive care unit. This can help to identify a patient who may benefit from more aggressive management (versus a patient who is up the CREEK without a paddle). The authors are from Ruhr University in Bochum, Germany.
Parameters:
(1) ALT in IU/L
(2) total cholesterol in mg/dL
(3) serum creatinine in mg/dL
(4) white blood cell count in 10^9/L
(5) serum sodium in mmol/L
(6) thrombocytosis
(7) thrombocytopenia
(8) BUN in mg/dL
(9) age in years
Parameter |
Finding |
Points |
---|---|---|
ALT in IU/L |
ALT in IU/L |
LN(ALT) |
cholesterol |
cholesterol in mg/dL |
ABS((cholesterol) - 225) |
creatinine |
<= 1.2 mg/dL |
0 |
|
> 1.2 mg/dL |
1 |
WBC |
as multiple of 10^9/L |
ABS((WBC) - 7.5) |
sodium |
>= 131 mmol/L |
0 |
|
< 131 mmol/L |
1 |
thrombocytosis |
<= 350 * 10^9/L |
0 |
|
> 350 * 10^9/L |
1 |
thrombocytopenia |
>= 150 * 10^9/L |
0 |
|
100 to 149 * 10^9/L |
1 |
|
50 to 99 * 10^9/L |
2 |
|
< 50 * 10^9/L |
3 |
BUN |
<11 mg/dL |
0 |
|
11 to 20 mg/dL |
1 |
|
21 to 30 mg/dL |
2 |
|
> 30 mg/dL |
3 |
age |
age in years |
(years) |
where:
• Several of the parameters are measures of organ failure.
X =
= (0.3942 * (points for ALT)) + (0.00999 * (points for cholesterol)) + (0.8133 * (points for creatinine)) + (0.0616 * (points for WBC count)) + (1.0227 * (points for sodium)) + (1.1881 * (points for thrombocytosis)) + (0.7783 * (points for thrombocytopenia)) + (0.3831 * (points for BUN)) + (0.0422 * (points for age)) - 8.6435
mortality risk =
= 1 / (1 + EXP((-1) * X))
Purpose: To predict mortality for a patient in the medical ICU using the Critical Risk Evaluation by Early Keys (CREEK) score of Stachon et al.
Specialty: Critical Care, Emergency Medicine, Clinical Laboratory
Objective: risk factors, severity, prognosis, stage
ICD-10: R57,