The Japanese Childhood Aplastic Anemia Study Group listed criteria for response to therapy in children with aplastic anemia.
Patient selection: pediatric moderate, severe or very severe aplastic anemia
Evaluation: at 6 months after starting therapy
Neutrophil Count
Platelet Count
Hemoglobin
Transfusion
Response
> 1,500 per µL
> 100,000 per µL
> 11.0 g/dL
not needed
complete
> 500 per µL
> 20,000 per µL
> 8.0 g/dL
partial (severe AA)
> 1,000 per µL
> 30,000 per µL
partial (moderate AA)
Relapse was defined as both of the following:
(1) return to blood counts consistent with moderate to severe aplastic anemia
(2) requirement for blood transfusions
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Specialty: Hematology Oncology, Clinical Laboratory
