Urban et al reported criteria for high bleeding risk for a patient undergoing percutaneous coronary intervention (PCI). The authors are from multiple institutions and members of the Academic Research Consortium for High Bleeding Risk.
High bleeding risk:
(1) Bleeding Academic Research Consertium (BARC) 3 or 5 bleeding risk with >= 4% at 1 year
(2) risk of intracranial hemorrhage >= 1% at 1 year
Major criteria:
(1) anticipated use of long-term oral anticoagulation (excluding vascular protection doses)
(2) eGFR < 30 mL per min (severe or end-stage CKD)
(3) hemoglobin < 11 g/dL
(4) spontaneous bleeding requiring hospitalization or transfusion in the past 6 months (if recurrent)
(5) baseline platelet count < 100,000 per µL (moderate or severe)
(6) chronic bleeding diathesis
(7) liver cirrhosis with portal hypertension
(8) active malignancy with the past 12 months (excluding non-melanoma skin cancer)
(9) previous spontaneous intracranial hemorrhage (ICH)
(10) previous traumatic intracranial hemorrhage within the past 12 months
(11) presence of a brain arteriovenous malformation
(12) moderate or severe ischemic stroke within the past 6 months
(13) nondeferrable major surgery on dual antiplatelet therapy (DAPT)
(14) recent major surgery or trauma within the past 30 days
Minor criteria (confers increased bleeding risk):
(1) age >= 75 years
(2) eGFR 30 to 59 mL/min
(3) hemoglobin 11 to 12.9 g/dL for men or 11 to 11.9 g/dLfor women
(4) spontaneous bleeding requiring hospitalization or transfusion within the past 12 months, not meeting the major criterion
(5) long-term use of oral NSAIDs or steroids
(6) any ischemic stroke at any time not meeting the major criterion