The American Academy of Neurology (AAN) AIDS Task Force developed criteria for a number of HIV-related neurologic conditions, including dementia.


Criteria - all 4 of the following:

(1) an acquired defect in cognitive abilities (see below):

(1a) defect persists for >= 1 month (based on reliable history and/or informant)

(1b) confirmation by neurologic, mental status and neurophysiological exam

(2) impairment as a result of the cognitive disorder (affecting work or activities of daily living)

(3) one or both of the following:

(3a) acquired abnormality of motor function or performance (incoordination, gait, fine motor skills, etc.)

(3b) acquired abnormality in behavior (motivation, emotional control, social behavior)

(4) absence of clouding of consciousness for a period sufficient to establish the defect in cognitive abilities



• The dementia complex can be subdivided into a motor-only or behavior-only type based on the findings in criterion 3.


The defect in cognitive abilities requires >= 2 of the following be affected:

(1) concentration or attention

(2) speed of information processing

(3) abstraction and reasoning

(4) visuospatial skills

(5) memory and learning

(6) speech and language


Diagnosis based on presence of an alternative diagnosis (other than HIV) that can explain the findings. These include fungal or parasitic CNS infection, substance abuse, psychiatric disorder, or malignancy.

Alternative Explanation









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