Criteria of Stasi et al for Response to Therapy for Immune Thrombocytopenic Purpura (ITP)

Stasi et al listed criteria for response to therapy in patients with immune thrombocytopenic purpura (ITP).

Parameters:

(1) initial platelet count per µL

(2) platelet count per µL after therapy

(3) need for continued therapy

increase in platelet count per µL =

= (platelet count after therapy) - (initial platelet count)

Platelet Count	Continued Therapy	Response
increased, and final count > 100,000 per µL	NA	complete response (CR)
increased, and final count >= 50,000 and < 100,000 per µL	NA	partial response(PR)
increased, and final count < 50,000 per µL	none needed	minor response (MR)
unchanged or decrease	NA	no response (NR)
increased and final count < 50,000 per µL	needed	no response (NR)

where:

• I will define an increase in platelet count as a final count > 1.1 * (initial count).

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