Shorvon and Ferlisi defined refractory and super-refractory convulsive status epilepticus (SE). The authors are from the UCL Institute of Neurology in London.
Patient selection: convulsive status epilepticus
Refractory convulsive status epilepticus - both of the following:
(1) failure of usual drug therapy
(2) general anesthesia is required to obtain control
Non-convulsive SE rarely requires general anesthesia for control.
Super-refractory convulsive status epilepticus - one or both of the following:
(1) refractory SE lasting >= 24 hours after starting general anesthesia
(2) refractory SE that recurs upon reducing or stopping general anesthesia
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