Criteria of Ozen et al for Diagnosis of Polyarteritis Nodosa in Childhood

• proteinuria, hematuria, and/or renal failure?

• myalgia and/or arthralgias?

• livedo reticularis, maculopapular purpuric lesions, or subcutaneous nodules?

• digital necrosis or peripheral gangrene?

• abdominal pain, GI bleeding or other gastrointestinal symptom?

• numbness, paresthesias, and/or polyneuropathy?

• central nervous system symptoms?

• hypertension?

• pericarditis, arrhythmias, cardiac failure, or myocardial infarction?

• pulmonary infiltrates, pleural effusion, or hemoptysis?

• fever, anorexia, fatigue or other constitutional symptoms?

• an elevated ESR or C-reactive protein level?

• leukocytosis?

• hepatitis B surface antigen (HBsAg) in the serum?

• antinuclear antibodies?

• anti-DNA antibodies?