Description

Neff et al evaluated criteria for the diagnosis of massive transfusion in pediatric patients. The authors are from Travis Air Force Base, San Antonio Military Medical Center, Uniformed Services University of the Health Sciences, Washington University and the Royal Centre for Defence Medicine (Birmingham).


Patient selection: combat-injured pediatric patient from 6 to 14 years

 

Parameters:

(1) volume of red blood cells transfuse in mL

(2) volume of FFP transfused in mL

(3) volume of platelets transfused in mL

(4) volume of cryoprecipitate in mL

(5) volume of whole blood in mL

(6) body weight in kg

 

total volume transfused =

= (volume of RBCs) + (volume of platelets) + (volume of FFP) + (volume of cryo) + (volume of whole blood)

 

total volume per kg body weight =

= (total volume transfused) / (body weight)

 

Interpretation:

A total volume of 40 mL/kg of all blood products during the first 24 hours is the cutoff above which there is significant mortality (early and in-hospital).

 

NOTE: The blood volume for a child ranges from 60-90 mL/kg, varying with age.


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